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Overdose of certain kinds of medications, like opioids, and certain brain, lung and muscle conditions can cause respiratory depression. The mainstay treatment for acute benzodiazepine toxicity is supportive care, which may include endotracheal intubation to provide definitive airway management. Single-dose or multi-dose activated charcoal, hemodialysis, or whole bowel irrigation play no role in managing benzodiazepine